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Chen Gong

Cheung Kong Young Scholar,Distinguished Young Scholars

Subject: Organic Chemistry

Address:LianheLou D503, NO. 94 Weijin Road, Tianjin 300071, China

Telephone: 022-83662300

E-Mail: gongchen@nankai.edu.cn


Research Interest:
Synthetic methodology, Total Synthesis, Carbohydrate chemistry, Medicinal Chemistry, Chemical Biology

1994-1998 Nanjing University
1999-2004 Columbia University, USA
2005-2008 Memorial Sloan-Kettering Cancer Center
2008-2015 The Pennsylvania State University
2015-present Nankai University

Honors and Awards:
2017,Distinguished Young Scholars
2014,Chinese-American Chemistry & Chemical Biology Professor Association (CAPA) Distinguished Junior Faculty Award
2013,Amgen Young Investigator Award
2012,Thieme Chemistry Journal Award
2011,National Science Foundation (NSF) CAREER Award

Selected publications:
1. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. A General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C-H Arylation. Nature Chem. 2017, accepted.
2. Guo-Xing Li, Cristian A Morales-Rivera, Fang Gao, Yaxin Wang, Gang He, Peng Liu,* and Gong Chen*. A Unified Ph otoredox-Catalysis Strategy for C(sp3)-H Hydroxylation and Amidation Using Hypervalent Iodine. Chem. Sci. 2017, 8, 7180-7185.
3. Hao Wang, Hua-Rong Tong, Gang He*, and Gong Chen*. An Enantioselective Bidentate Auxiliary Directed Palladium- Catalyzed Benzylic C H Arylation of Amines Using a BINOL Phosphate Ligand. Angew. Chem., Int. Ed. 2016, 55, 15387-15391.
4. Guo-Xing Li, Cristian A Morales-Rivera, Yaxin Wang, Fang Gao, Gang He, Peng Liu,* and Gong Chen*. Photoredox-Mediated Minisci C–H Alkylation of N-Heteroarenes Using Boronic Acids and Hypervalent Iodine. Chem. Sci. 2016, 7, 6407-6412.
5. Gang He,* Gang Lu, Zhengwei Guo, Peng Liu,* and Gong Chen*. Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C-H Amination. Nature Chem. 2016, 8, 1131-1136.
6. Gang He, Bo Wang, William A Nack, and Gong Chen*. Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C-H Functionalization. Acc. Chem. Res. 2016, 49, 635-645.
7. Bo Wang, Yunpeng Liu, Rui Jiao, Yiqing Feng, Qiong Li, Chen Chen, Long Liu, Gang He, and Gong Chen*. Total Synthesis of Mannopeptimycins α and β. J. Am. Chem. Soc. 2016, 138, 3926-3932,
8. Yaxin Wang, Guo-Xing Li, Guohui Yang, Gang He, and Gong Chen*. A Visible-Light-Promoted Radical Reaction System for Azidation and Halogenation of Tertiary Aliphatic C-H Bonds. Chem. Sci. 2016, 7, 2679-2683.