Name
He Zhengjie
Gender
Male
Academic Background
Doctor degree
Graduate School
Nankai University
Professional Title
professor
Administrative Post
deputy director of department
Department/Institute
Department of Chemistry
Special Talent
Address
94 Weijin Road
Telephone
022-23501520
Email
zhengjiehe@nankai.edu.cn
Research Group Website
http://skleoc.nankai.edu.cn/professors/hezhengjie/hezj.htm
Research Interest
Research Interest Areas:
1. Organophosphorus Chemistry;
2. Organic Synthetic Chemistry;
3. Medicinal Chemistry



History
1985-1989,Central China Normal University, Chemistry Dept., undergraduate
1989-1994,Institute of Elemento-Organic Chemistry, Nankai University, graduate
1994-1998,Nankai University, associate professor
1998-2004,University of Pretoria (SA, 1998-1999), Marquette University (USA, 1999-2003), Purdue University (USA, 2003-2004), postdoctoral associate
2004 to present,Chemistry College, Nankai University, professor




Honors and Awards
none




Scientific Achievements & Selected Publications
More than 120 peer-reviewed research papers have been published.Selected publications are listed as follows.
1. Enantioselective [4+1] annulation of α,β-unsaturated imines with allylic carbonates catalyzed by a hybrid p-chiral phosphine oxide-phosphine, H. Li, J. Luo, B. Li, X. Yi, Z. He, Org. Lett. 2017, 19, 5637-5640.
2. P(NMe2)3-mediated reductive (1+4) annulation reaction of isatins with nitroalkenes: an access to spirooxindolyl isoxazoline N-oxides and their corresponding isoxazolines, Y. Liu, H. Li, X. Zhou, Z. He, J. Org. Chem. 2017, 82, 10997-11007.
3. Phosphine-catalyzed (4 + 1) annulation of o-hydroxyphenyl and o-aminophenyl ketones with allylic carbonates: syntheses and transformations of 3-hydroxy-2,3-disubstituted dihydrobenzofurans and indolines, Z. Qin, W. Liu, D. Wang, Z. He, J. Org. Chem. 2016, 81, 4690-4700.
4. Divergent reactivity of nitrocyclopropanes with Huisgen zwitterions and facile syntheses of 3-alkoxy pyrazolines and pyrazoles, C. Yang, W. Liu, Z. He, Z. He, Org. Lett. 2016, 18, 4936-4939.
5. Annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and its applications in the syntheses of pyrrolo[4,3,2-de]quinolinones and marine alkaloids Ammosamides, C. Yang, X. Chen, T. Tang, Z. He, Org. Lett. 2016, 18, 1486-1489.
6. P(NMe2)3-mediated reductive [1 + 4] annulation of isatins with enones: facile synthesis of spirooxindole-dihydrofurans, R. Zhou, K. Zhang, Y. Chen, Q. Meng, Y. Liu, R. Li, Z. He, Chem. Commun. 2015, 51, 14663-14666.
7. Diastereoselective synthesis of functionalized spirocyclopropyl oxindoles via P(NMe2)3-mediated reductive cyclopropanation, R. Zhou, C. Yang, Y. Liu, R. Li, Z. He, J. Org. Chem., 2014, 79, 10709-10715.
8. Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes, M. Yang, T. Wang, S. Cao, Z. He, Chem. Commun. 2014, 50, 13506-13509.




Professional Cultivation
Qualified for supervising MS and PhD graduates. More than 20 graduates have been rewarded Master degree or Ph.D in organic chemistry.