He Zhengjie
Academic Background
Doctor degree
Graduate School
Nankai University
Professional Title
Administrative Post
deputy director of department
Department of Chemistry
Special Talent
94 Weijin Road
Research Group Website
Research Interest
Research Interest Areas:
1. Organophosphorus Chemistry;
2. Organic Synthetic Chemistry;
3. Medicinal Chemistry

1985-1989,Central China Normal University, Chemistry Dept., undergraduate
1989-1994,Institute of Elemento-Organic Chemistry, Nankai University, graduate
1994-1998,Nankai University, associate professor
1998-2004,University of Pretoria (SA, 1998-1999), Marquette University (USA, 1999-2003), Purdue University (USA, 2003-2004), postdoctoral associate
2004 to present,Chemistry College, Nankai University, professor

Honors and Awards

Scientific Achievements & Selected Publications
More than 120 peer-reviewed research papers have been published.Selected publications are listed as follows.
1. Enantioselective [4+1] annulation of α,β-unsaturated imines with allylic carbonates catalyzed by a hybrid p-chiral phosphine oxide-phosphine, H. Li, J. Luo, B. Li, X. Yi, Z. He, Org. Lett. 2017, 19, 5637-5640.
2. P(NMe2)3-mediated reductive (1+4) annulation reaction of isatins with nitroalkenes: an access to spirooxindolyl isoxazoline N-oxides and their corresponding isoxazolines, Y. Liu, H. Li, X. Zhou, Z. He, J. Org. Chem. 2017, 82, 10997-11007.
3. Phosphine-catalyzed (4 + 1) annulation of o-hydroxyphenyl and o-aminophenyl ketones with allylic carbonates: syntheses and transformations of 3-hydroxy-2,3-disubstituted dihydrobenzofurans and indolines, Z. Qin, W. Liu, D. Wang, Z. He, J. Org. Chem. 2016, 81, 4690-4700.
4. Divergent reactivity of nitrocyclopropanes with Huisgen zwitterions and facile syntheses of 3-alkoxy pyrazolines and pyrazoles, C. Yang, W. Liu, Z. He, Z. He, Org. Lett. 2016, 18, 4936-4939.
5. Annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and its applications in the syntheses of pyrrolo[4,3,2-de]quinolinones and marine alkaloids Ammosamides, C. Yang, X. Chen, T. Tang, Z. He, Org. Lett. 2016, 18, 1486-1489.
6. P(NMe2)3-mediated reductive [1 + 4] annulation of isatins with enones: facile synthesis of spirooxindole-dihydrofurans, R. Zhou, K. Zhang, Y. Chen, Q. Meng, Y. Liu, R. Li, Z. He, Chem. Commun. 2015, 51, 14663-14666.
7. Diastereoselective synthesis of functionalized spirocyclopropyl oxindoles via P(NMe2)3-mediated reductive cyclopropanation, R. Zhou, C. Yang, Y. Liu, R. Li, Z. He, J. Org. Chem., 2014, 79, 10709-10715.
8. Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes, M. Yang, T. Wang, S. Cao, Z. He, Chem. Commun. 2014, 50, 13506-13509.

Professional Cultivation
Qualified for supervising MS and PhD graduates. More than 20 graduates have been rewarded Master degree or Ph.D in organic chemistry.