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Name
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Chan Cao |
Gender
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Female |
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Academic Background
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Doctor degree |
Graduate School
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Nankai University |
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Professional Title
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researcher |
Administrative Post
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Department/Institute
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Institute of Elemento-organic Chemistry |
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Special Talent
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Nankai University Hundred Young Academic Leaders Program |
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Address
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109 South Building of Chemistry, Nankai University, 94 Weijin Road |
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Telephone
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Email
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chancao@nankai.edu.cn |
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Research Group Website
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Research Interest
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Chemical Biology:
Dr. Cao seeks to tackle important problems across a wide range of biomedical sciences including ion channel mechanism, protein-drug interaction, and cancer immunotherapy. |
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History
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2006—2010, B.S., Chemistry Department of Qufu Normal University
2010—2013, M.S., State Key Laboratory of Elemento-Organic Chemistry, Chemistry Department of Nankai University
2013—2017, Ph.D., State Key Laboratory of Elemento-Organic Chemistry, Chemistry Department of Nankai University
2014—2017, Joint-Ph.D., The Department of Biological Chemistry and Molecular Pharmacology, Harvard University Medical School
2017—2019, Postdoctoral Research Fellow, The Department of Biological Chemistry and Molecular Pharmacology, Harvard University Medical School |
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Honors and Awards
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2019, Harvard Medical School CSSA Outstanding Leadership Award |
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Scientific Achievements & Selected Publications
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Dr. Cao has published Nature 2016, PNAS 2017, Advanced Science 2019 et al as first-author or co-first author in the last five years, and her scientific papers were cited by more than 360 times.
Five Representative Publication:
[1] Cao Chan; Wang Shuqing; Cui Tanxing; Su Xun Cheng*; Chou James J*; Ion
and inhibitor binding of the double-ring ion selectivity filter of the
mitochondrial calcium uniporter , Proceedings of the National Academy of
Sciences of the United States of America, 2017, 114(14): E2846-E2851.
[2] Oxenoid, Kirill#; Dong, Ying#; Cao, Chan#; Cui, Tanxing#; Sancak,
Yasemin; Markhard, Andrew L.; Grabarek, Zenon; Kong, Liangliang; Liu, Zhijun;
Ouyang, Bo; Cong, Yao; Mootha, Vamsi K.; Chou, James J.*; Architecture of the
mitochondrial calcium uniporter , Nature, 2016, 533(7602): 269-273.
[3] Pan, Liqiang#; Cao, Chan#; Run, Changqing; Zhou, Liujuan; Chou, James J.*
; DNA-Mediated Assembly of Multispecific Antibodies for T Cell Engaging and
Tumor Killing , Advanced Science, 2020, 7(2): 1900973.
[4] Cao, Chan; Chen, Jia-Liang; Yang, Yin; Huang, Feng; Otting, Gottfried;
Su, Xun-Cheng*; Selective N-15-labeling of the side-chain amide groups of
asparagine and glutamine for applications in paramagnetic NMR spectroscopy , J
ournal of Biomolecular NMR, 2014, 59(4): 251-261.
[5] Yuan, Yuan#; Cao, Chan#; Wen, Maorong; Li, Min; Dong, Ying; Wu, Lijie;
Wu, Jian; Cui, Tanxing; Li, Dianfan*; Chou, James J.*; OuYang, Bo*; Structural
Characterization of the N-Terminal Domain of the Dictyostelium discoideum
Mitochondrial Calcium Uniporter , ACS Omega, 2020, 5(12): 6452-6460. |
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Professional Cultivation
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Per year:
two master graduates, two Ph.D. graduates
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